Jun 1, 2020 · Supplementary information is available for this paper at https://doi.org/10.1038/s41586-020-2399-1. Competing interests The authors declare no ...

Search life-sciences literature (41,956,878 articles, preprints and more) · Desymmetrization of difluoromethylene groups by C-F bond activation.

Publisher: Nature Publishing Group ; Document Type: Report ; Length: 4,686 words ; Lexile Measure: 1600L ; DOI: http://dx.doi.org/10.1038/s41586-020-2399-1 ...

Subsequently, we investigated how the electronic nature of the allyl fluoride influenced the reaction outcome. ... (c) Cheng Q. ... doi: 10.1038/s41586-020-2399-1.

Jan 7, 2014 · A first example of Pd-catalyzed gem-difluoroallylation of organoborons using 3-bromo-3,3-difluoropropene (BDFP) in high efficiency with high ...

Sep 23, 2021 · This protocol extends to aryl iodides, chlorides, and triflates, as well as substituted difluoroallyl boronates, providing a versatile synthesis ...

Oct 28, 2020 · Nature 2020, 583, 548– 553, DOI: 10.1038/s41586-020-2399-1. Google Scholar. 10e. Desymmetrization of difluoromethylene groups by C-F bond ...

Apr 30, 2024 · The aromatic difluoromethyl group (Ar-CF2H) is an emerging functional group found in pharmaceutical compounds.

May 1, 2024 · The trifluoromethyl group has a profound influence on the overall properties of molecules in terms of hydrophilicity and polarity. It has been ...

Oct 10, 2023 · Herein, we have successfully developed a Pd/Cu/Li ternary system for stereodivergent synthesis of chiral fluorinated amino acids. This method ...