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Dysregulation of the PHD finger activities can occur as a result of its deletion, from mutations in the histone binding site, or mutations in the canonical ...
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In this review, we will discuss the structural features of PHD fingers as well as the diseases for which direct mutation or dysregulation of the PHD finger has ...
Missing: q= https% 2Fwww. 2Ffigure% 2FPHD- result_fig3_40847029
Dysregulation of the PHD finger activities can occur as a result of its deletion, from mutations in the histone binding site, or mutations in the canonical ...
Missing: q= 2Fwww. researchgate. 2Ffigure% 2FPHD- result_fig3_40847029
3 When dysregulated, numerous PHD fingers have been implicated in human diseases, including immunological disorders, neurological diseases, and cancers. 4 For ...
Missing: q= https% 2Fwww. 2Ffigure% 2FPHD- result_fig3_40847029
Jul 17, 2008 · In this review, we will discuss the structural features of PHD fingers as well as the diseases for which direct mutation or dysregulation of the ...
Missing: 2Fwww. researchgate. 2Ffigure% 2FPHD- result_fig3_40847029
Dysregulated PHD fingers are implicated in various human diseases, including acute myeloid leukemia. Targeting PHD fingers with small molecules is considered ...
Missing: q= https% 2Fwww. 2Ffigure% 2FPHD- result_fig3_40847029
One molecular mechanism that regulates access to genetic information includes recognition of histone modifications, which is carried out by protein modules that ...
Missing: q= https% 2Fwww. 2Ffigure% 2FPHD- result_fig3_40847029
This chapter summarizes functional investigations of the PHD finger, with a focus on studies elucidating the molecular mechanism of action. The role of this ...
Missing: q= https% 2Fwww. 2Ffigure% 2FPHD- Dysregulation- result_fig3_40847029
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