Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis ... Hartmut Weiler. 1Blood ...
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Is thrombomodulin an anticoagulant?
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What is the protein C anticoagulation pathway?
The PC pathway is a major anticoagulant mechanism that downregulates thrombin formation and hedges thrombus formation. The objectives of this review were to ...
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First and foremost, APC is a natural anticoagulant in that it suppresses further thrombin formation by proteolytically destroying coagulation factors Va and ...
Nov 5, 2020 · Objective: The objective of this study was to determine the capacity of the TM-augmented CAT to detect defects in various protein C system ...
Mar 8, 2021 · Thrombomodulin (TM) is a thrombin receptor on endothelial cells that is involved in promoting activation of the anticoagulant protein C pathway ...
A new anticoagulation strategy using recombinant human thrombomodulin in patients on veno-venous extracorporeal membrane oxygenation: a retrospective study.
Thrombomodulin (TM) is an endothelial glycoprotein that plays a dual role in maintaining healthy endothelium-as a natural anticoagulant by binding thrombin to ...
Mar 8, 2021 · Thrombomodulin (TM) is a thrombin receptor on endothelial cells that is involved in promoting activation of the anticoagulant protein C pathway ...
Summary. Background: The assessment of the risk of recurrent venous thromboembolism (VTE) is important to determine the optimal duration of secondary ...
provides a natural anticoagulant mechanism that inhibits the activity and excessive generation of the blood coagulation protease thrombin (1, 2). The associ ...