Three states for the Hedgehog pathway, for Cubitus interruptus, and for Hedgehog target genes. In the nucleus, the repressor form of Cubitus interruptus ...
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The Gli homolog Cubitus interruptus (Ci) is involved in controlling the transcription of Drosophila Hh target genes and thus represents the most downstream ...
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We interpret this as evidence against the existence of Ci-independent branches in the Hh signal transduction pathway and propose that most cases of apparent Ci/ ...
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Following the discovery of Hh signaling activation in Gorlin syndrome, increasing evidence suggests that Hh signaling is frequently activated in human cancer.
We show that Ci is a sequence-specific DNA binding protein that drives transcription from the wg promoter in transiently transfected cells. We demonstrate that ...
Missing: https% 2Fwww. 2Ffigure% states- target_fig3_7933273
This review will focus on the regulation of canonical hedgehog signalling, from expression of the ligand through to the activation of target genes. 2. Hedgehog ...
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