Sep 28, 2022 · Activation of RAS is crucial in driving cellular outcomes including proliferation, differentiation, migration and apoptosis via the MAPK pathway ...
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Sep 28, 2022 · This complex is mediated by the adaptor protein, growth factor receptor bound protein 2 (Grb2). Grb2 consists of two Src homology 3 (SH3) ...
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Sep 13, 2022 · Activation of RAS is crucial in driving cellular outcomes including proliferation, differentiation, migration and apoptosis via the MAPK ...
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How does GRB2 activate ras?
... The Grb2 isoform, Grb3-3, negatively regulates Ras activation · Communications Biology · Behind the Paper · The Grb2 isoform, Grb3-3, negatively regulates Ras ...
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New research indicates that variations in the configuration of GRB3-3 might play a role in negatively regulating the MAPK signaling pathway and efficiently ...
Dec 12, 2021 · Control experiments without ATP confirm that the EGFRTAIL:Grb2 condensate is dependent on EGFR phosphorylation (Figure 4E). EGFR condensation ...
Sep 28, 2022 · Activation of RAS is crucial in driving cellular outcomes including proliferation, differentiation, migration and apoptosis via the MAPK pathway ...
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