Sep 27, 2023 · 001976 NOD/ShiLtJ The NOD/ShiLtJ strain (commonly called NOD) is a polygenic model for autoimmune type 1 diabetes. Diabetes in NOD mice is ...
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People also ask
How much do NOD mice cost?
Age in Weeks | Quantity 1 - 999 |
3 to 4 | $119.00 |
5 to 7 | $150.00 |
8 to 9 | $181.00 |
Why do NOD mice develop diabetes?
NOD mice have a mutation in exon 2 of the CTLA-4 gene, which causes it to be spliced incorrectly. CTLA-4 plays a major role in suppressing the T-cell immune response. Without the proper functioning of CTLA-4, T-cells attack the insulin producing cells. This results in Type 1 Diabetes.
What is the history of the NOD mouse?
NOD inbred mice originated early on in the inbreeding of the Cataract Shionogi (CTS) strain. These mice were originally outbred Jcl:ICR mice. At F6, the progenitors of the future NOD/Shi mice were inbred on the basis of an elevated fasting blood glucose level in cataract-free mice.
Sep 27, 2023
001976 NOD/ShiLtJ The NOD/ShiLtJ strain (commonly called NOD) is a polygenic model for autoimmune type 1 diabetes. Diabetes in NOD mice is characterized by ...
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JAX® Mice Strain - NOD/ShiLtJ ... Groups of 120 female and 80 male mice were weighed weekly. Mice were fed a diet containing 6% fat (LabDiet 5K52 formulation).
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Missing: sa= %22q% 3D% 22 001976
Jan 14, 2024 · Ts65Dn mice are trisomic for about two-thirds of the genes orthologous to human chromosome 21 and are a well-characterized model for studying ...
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May 1, 2019 · Strain #:005557 ; Common Name: NSG ; Important Note: Like its parental strain, NOD/ShiLtJ (Stock No. 001976), NSG mice exhibit a progressive ...
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Jan 3, 2019 · Primitive hematopoietic stem cells from C57BL/6J mice show greatly delayed senescence relative to BALB/c and DBA/2J. This is a dominant trait.
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Aug 5, 2021 · NOR/LtJ mice are matched at the diabetogenic H2g7 complex to NOD/ShiLtJ. In addition to serving as controls to the NOD/ShiLtJ strain, these mice ...
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